The effect of 40 Hz Sound Stimulation on the Recovery of Brain Injury Coma

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR1900026101

Enrollment

Unknown

Registered

2019-09-21

Start date

2020-01-01

Completion date

Unknown

Last updated

2019-09-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Brain Injury

Interventions

Group 1:40 Hz sound stimulation

Group 2:conventional sound stimulation

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: (1) History of head trauma, confirmed by cranial imaging examination, and trauma occurred 48 hours before admission; (2) Aged 18 to 65 years; (3) admission examination is coma, Grasse score ( Glasgow Coma Scale, GCS) <=8 points; (4) coma after injury for more than 5 hours.

Exclusion criteria

Exclusion criteria: 1. Those with severe basal diseases such as cerebral infarction, crown disease, diabetes, chronic obstructive pulmonary disease, liver and kidney failure; 2. incomplete patient data, abandon treatment in the middle; 3. serious patients during observation and treatment Vital signs, irreversible brain stem damage, respiratory and circulatory failure, and serious complications such as high fever and infection; 4. Withserious diseases of the central nervous system and cerebrovascular diseases in the past medical history.

Design outcomes

Primary

Measure	Time frame
GCS;BAEP;SEP;EEG;	—

Secondary

Measure	Time frame
BABA;S100B;	—

Countries

China

Contacts

Public ContactZhou Chaosheng

Shanghai Tenth People's Hospital

shsykfk@163.com+86 19921603125

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026