Effect of ropivacaine on tracheal surface anesthesia on stress response during intracranial aneurysm clipping

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR1900026058

Enrollment

Unknown

Registered

2019-09-20

Start date

2019-10-25

Completion date

Unknown

Last updated

2019-09-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Intracranial aneurysm

Interventions

Ropivacaine group:Ropivacaine tracheal surface anesthesia

Lidocaine group:Lidocaine tracheal surface anesthesia

Normal saline group:Normal saline

Eligibility

Sex/Gender

All

Age

18 Years to 65 Years

Inclusion criteria

Inclusion criteria: The age ranged from 18 to 65 years. The American Society of Anesthesiologists (ASA) graded I to II, Glasgow graded 14 to 15, and Cormack laryngoscope exposure graded I to II.

Exclusion criteria

Exclusion criteria: Cardiovascular disease, respiratory insufficiency, diabetes mellitus, liver and kidney insufficiency, morbid obesity, epilepsy, history of using vasoactive drugs and psychotropic drugs.

Design outcomes

Primary

Measure	Time frame
Perioperative blood pressure ;	—

Secondary

Measure	Time frame
Blood sugar;Cortisol;Spontaneous breathing recovery time ;Extubation time;Recovery time;Number of cases and degree of cough ;Alert sedation score after extubation ;Resuscitation agitation score ;	—

Countries

China

Contacts

Public ContactHaixia Gong

The First Affiliated Hospital of Nanchang University

13870981388@139.com+86 13870891388

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026