Postoperative Dilirum and Postoperative Cognitive Dysfunction
Conditions
Interventions
preoperative sedation group:sedative medicine
preoperative high anxiety group
preoperative low anxiety group:N/A
Sponsors
The First Affiliated Hospital of University of Science and Technology of China
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: Aged 18-75 year, no gender limitation, patients undergoing selected surgery, ASA ranged II to III.
Exclusion criteria
Exclusion criteria: The patients with pyschological disease and cognitive dysfunction before surgery; the disabled patients with listening and motion;the patients with a long history of psychological medicine administration.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| the incidence of postoperative dilirium;The incidence of postoperative cognitive dysfunction;the serum level of MMP-9; | — |
Secondary
| Measure | Time frame |
|---|---|
| the serum level of TNF-a;the serum level of IL-1ß;the serum level of IL-6;the serum level of MMP-9; | — |
Countries
China
Contacts
Public ContactXiaoqing Chai
The First Affiliated Hospital of University of Science and Technology of China
Outcome results
None listed