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Effects of equal volume control ventilation and equal pressure controlled ventilation on pulmonary function in pediatric liver transplantation

Clinical study for lung protection in pediatric liver transplantation

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR1900026016
Enrollment
Unknown
Registered
2019-09-18
Start date
2019-09-30
Completion date
Unknown
Last updated
2019-09-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

liver transplantation

Interventions

volume controlled ventilation group:6-8ml/kg ventilation
pressure controlled ventilation group:8mmHg

Sponsors

Tianjin First Center Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
1 Years to 12 Years

Inclusion criteria

Inclusion criteria: 1. Liver transplant patients aged 1 to 12 years; 2. ASA grade II or III; 3. Liver function Child-Pugh grade B~C grade; 4. Classical non-circulating orthotopic liver transplantation;

Exclusion criteria

Exclusion criteria: 1. Combined hepatopulmonary syndrome with moderate to severe pulmonary hypertension; 2. Combined cardiac dysfunction, renal failure; 3. Upper respiratory tract infection, lung infection or respiratory failure occurred within 4 weeks before surgery; 4. Prolonged ventilator assist time due to surgical complications.

Design outcomes

Primary

MeasureTime frame
PaO2/FiO2;Dynamic compliance of the lung;Postoperative pulmonary complications;—

Countries

China

Contacts

Public ContactJia Lili

Tianjin First Center Hospital

jialili19880801@163.com+86 13102058301

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026