Role and mechanism of TXNIP on Th9 cells activation in the pathogenesis of chronic rhinosinusitis

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Observational

Source

ChiCTR

Registry ID

ChiCTR1900026011

Enrollment

Unknown

Registered

2019-09-17

Start date

2019-10-01

Completion date

Unknown

Last updated

2019-09-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

chronic rhinosinusitis

Interventions

healthy control group:None

CRSwNP group:None

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: The diagnostic criteria for chronic sinusitis with nasal polyps refer to the 2012 EPOS diagnostic criteria.

Exclusion criteria

Exclusion criteria: 1. No oral glucocorticoid hormone was taken within 3 months before surgery, and no corticosteroid nasal spray was used within one month before surgery; 2. Patients with chronic sinus disease other than nasal polyps, allergic rhinitis and localized allergic rhinitis are excluded; 3. Unilateral nasal polyps and nasal polyps with fungal diseases are excluded.

Design outcomes

Primary

Measure	Time frame
Nasal endoscope;CT score;TXNIP, NLRP3;	—

Countries

China

Contacts

Public ContactWei-tian Zhang

Shanghai Sixth People's Hospital

drzhangwt@163.com+86 021-24058706

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026