Malnourished tumor patients
Conditions
Interventions
Group 1:feeding Nuobaoneng powder
Group 2:feeding Ruineng TPF-T
Sponsors
Beijing Cancer Hospital
Eligibility
Sex/Gender
All
Age
10 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Subjects were diagnosed as malignant tumors by pathology or cytology within 8 weeks prior to enrollment. Patients, including cachexia, anorexia, chewing and dysphagia; 2. According to the investigator's judgment, patients requiring nutritional therapy: (NRS2002 total score >=3 points or PG-SGA >=4 points or estimated to be unable to eat 60% of the recommended energy intake for more than one week); 3. Subjects are laboratory tested and meet the following criteria: (1) blood routine: hemoglobin >=90g/L, absolute neutrophil count (ANC >=1.5x10^9/L, platelets >=100x10^9/L; (2) liver and kidney function: ALT, AST =30g / L; 4. Ages over 10 years old, male and female and ethnic groups are not limited; 5. Expected survival period >=3 months; 6. Those who voluntarily participate in clinical trials and sign informed consent.
Exclusion criteria
Exclusion criteria: 1. Patients who do not require artificial nutritional support; 2. Patients who have undergone parenteral nutrition at the same time; 3. All patients who are not suitable for enteral nutrition, such as patients with digestive tract spasm, gastrointestinal bleeding, complete intestinal obstruction, severe diarrhea and other patients with severe digestive dysfunction; 4. Patients who are unable to meet the prescribed doses as required, such as postoperative, radiotherapy, chemotherapy, and patients with severe nausea and vomiting; 5. Severe liver and kidney dysfunction; 6. Patients using coumarin anticoagulants and immunological preparations; 7. Those who have been receiving systemic steroids for a long time (Note: short-term user withdrawal > 2 weeks can be selected); 8. Patients who have taken fish oil (pure fish oil products) within 4 weeks or participated in other clinical trials; 9. Drugs (such as glucocorticoids, etc.) that the investigator believes may affect the therapeutic effect; 10. Patients with other serious organ diseases; 11. Combine people with poorly controlled endocrine, metabolic and immune system diseases; 12. Those who have congenital metabolic disorders and substances allergic to the known ingredients of the test food for the substances contained in this product; 13. Women who are pregnant or preparing for pregnancy, lactating women; 14. Patients with poor adherence or who the investigator believes are not suitable for the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Lean body mass; | — |
Secondary
| Measure | Time frame |
|---|---|
| Grip strength, protein, nutrient intake; | — |
Countries
China
Contacts
Public ContactFang Yu
Beijing Cancer Hospital
Outcome results
None listed