acute pancreatitis
Conditions
Interventions
experimental group: hydromorphone 10mg(2ml:2mg) mixed with 0.9% saline to a volume dose of 200mL
controlled group:Pethidine 50mg im, when required
Sponsors
West China Hospitial, Sichuan University
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: (1) diagnosed with AP; (2) having AP for less than 5 days; (3) the VAS score at admission is greater than or equal to 5; (4) aged 18-70 years; (5) With the informed consent of the patient or his legal representative, voluntary subjects and sign the informed consent.
Exclusion criteria
Exclusion criteria: 1. pregnant or nursing women; 2. patients with other serious organ diseases: patients with coronary heart disease or severe heart failure, severe liver and kidney dysfunction, anemia, granulocytosis and other blood system diseases, patients with mental diseases and consciousness disorders, and patients with tumors; 3. history of mental illness; 4. chronic pancreatitis, traumatic pancreatitis; 5. have hypersensitivity to hydromorphone or any component of the preparation (including sulfites), dieletine; We have acute or severe bronchial asthma and severe pulmonary dysfunction, paralytic ileus, supraventricular tachycardia, craniocerebral injury, intracranial space-occupying lesions in patients.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Visual Analog Scale;Area Under the Pain Curve; | — |
Secondary
| Measure | Time frame |
|---|---|
| hospital days;consumption of pethidine;hospital satisfaction score;changes of blood index; | — |
Countries
China
Contacts
Public ContactKun Jiang
West China Hospitial, Sichuan University
Outcome results
None listed