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A clinical study for the efficacy and safety of a multicenter, open, randomized, low-dose aspirin for prevention of deep vein thrombosis after PICC catheterization

A clinical study for the efficacy and safety of a multicenter, open, randomized, low-dose aspirin for prevention of deep vein thrombosis after PICC catheterization

Status
Recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR1900025948
Enrollment
Unknown
Registered
2019-09-15
Start date
2019-09-16
Completion date
Unknown
Last updated
2019-09-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Deep Vein Thrombosis

Interventions

Intervention group:oral low-dose Aspirin
Control group:No oral aspirin

Sponsors

The Fifth Affiliated of Sun Yat-Sen University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 85 Years

Inclusion criteria

Inclusion criteria: Patients who underwent PICC tube placement in the Cancer Center of the Fifth Hospital of Sun Yat-sen University from September 2019 to September 2021 were selected. All patients are required to meet conditions (1) to (5). (1) Aged 18-85 years, male or female; (2) VTE risk assessment >= 3 points and <= 15 points; (3) No history of upper extremity vascular disease; (4) There is no history of PICC placement; (5) Patients who require chemotherapy according to their condition; (6) Patients voluntarily sign informed consent.

Exclusion criteria

Exclusion criteria: (1) Previous thrombosis occurred; (2) Patients with thrombocytopenic purpura, aplastic anemia, hemophilia, and mediterranean thrombocytopenia; (3) Those with coagulopathy; (4) There is currently a history of active ulcer or gastrointestinal bleeding; (5) Patients who need long-term use of warfarin and anticoagulant drugs such as heparin; (6) Those who have had a history of allergies to aspirin; (7) Patients considered by the investigator not suitable for inclusion.

Design outcomes

Primary

MeasureTime frame
thrombosis yes/no;

Countries

China

Contacts

Public ContactRongzhi Xie; Linjuan Zeng

The Fifth Affiliated of Sun Yat-Sen University

xierzhi@mail.sysu.edu.cn+86 13727088841

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026