Effect of Lactobacillus rhamnosus on the prevention of feeding intolerance in premature infants

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR1900025945

Enrollment

Unknown

Registered

2019-09-15

Start date

2020-01-01

Completion date

Unknown

Last updated

2019-09-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Feeding intolerance in premature infants

Interventions

treatment group:Lactobacillus rhamnosus probiotic powder+ premature formula milk

control group:premature formula milk

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: (1) The gestational age is less than 37 weeks and the birth weight is less than 2000 g; (2) Income 24 hours after birth in our department; (3) Parents are willing to participate in this study and sign the informed consent form for clinical research.

Exclusion criteria

Exclusion criteria: Neonatal sepsis, necrotizing enterocolitis (NEC), hereditary and metabolic diseases, congenital gastrointestinal malformations and discharges in advance were excluded.

Design outcomes

Primary

Measure	Time frame
Incidence of feeding intolerance;	—

Secondary

Measure	Time frame
Incidence of vomiting;Incidence of abdominal distension;Incidence of gastric retention;Time needed to regain birth weight;Time needed to total gastrointestinal feeding;Weight gain rate;Average length of stay;	—

Countries

China

Contacts

Public ContactFang Chengzhi

Renmin Hospital of Wuhan University

fcz2000@126.com+86 18120410060

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026