hypertension
Conditions
Interventions
Control group:FTZ simulant, 4 capsules each time, 3 times a day.
Sponsors
The First Affiliated Hospital of Guangdong Pharmaceutical University
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: 1. Aged 18 to 60 years, male or female; 2. Patients with essential hypertension meet the diagnostic criteria for hypertension, systolic blood pressure < 160mmHg and/or diastolic blood pressure <100mmHg; 3. The stratification of cardiovascular risk levels belongs to low- and medium-risk groups; 4. Patients who have not taken antihypertensive drugs for the first time or have not taken antihypertensive drugs within one month; 5. The patient agrees to sign the informed consent form.
Exclusion criteria
Exclusion criteria: 1. Transaminase AST or ALT is greater than 2 times the upper limit of normal, serum creatinine or blood urea nitrogen is greater than the upper limit of normal; 2. Have mental illness; 3. Women during pregnancy or lactation; 4. Patients who have participated in other drug clinical trials or are participating in other clinical trials within 3 months prior to the trial.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The 8th week (or the last evaluation) blood pressure compliance rate, the absolute value of blood pressure changes.; | — |
Secondary
| Measure | Time frame |
|---|---|
| At 8th Week (or last visit) assess the pulse pressure (PP) change absolute value;at 8th Week (or last visit) valley/peak ratio change;Vascular endothelial function;Insulin sensitivity index;BNP;compound F;PRA;Ang II;ALD; | — |
Countries
China
Contacts
Public ContactGuo Jiao
Guangdong Pharmaceutical University
Outcome results
None listed