acute ischemic stroke
Conditions
Interventions
Control group:Aspirin and/or Clopidogrel
Sponsors
The Affiliated Weihai Central Hospital of Qingdao University
Eligibility
Sex/Gender
All
Age
18 Years to 85 Years
Inclusion criteria
Inclusion criteria: 1) Age >=18 years old; 2) The time from onset or waking stroke (from the onset of sleep to the onset time) to the time of treatment within 48 hours; 3) Diagnosis of acute cerebral infarction or transient ischemic attack based on clinical symptoms or head CT or MRI assessment; 4) According to the clinical signs and symptoms at the time of onset, the NIHSS score is <=15 points; 5) receiving treatment with tirofiban or aspirin or clopidogrel.
Exclusion criteria
Exclusion criteria: 1) Confirmation of intracranial hemorrhage by head CT or MRI; 2) mRS score >=2 points before onset; 3) pregnant or lactating women; 4) Allergic to tirofiban and contrast agents; 5) combined with severe infection or cardiopulmonary insufficiency; 6) blood glucose 22.2mmol/L (400mg / dl), platelets 200mmol/L (2.5mg/dl); 9) The life expectancy of any disease is <6 months in the late stage; 10) Imaging exists brain tumors with a placeholder effect.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 90d mRS score;Incidence of symptomatic intracranial hemorrhage within 48 hours;90 d mortality; | — |
Secondary
| Measure | Time frame |
|---|---|
| 90 d mRS score 0-2 points (%);The NIHSS score changed 24 h after treatment;;The NIHSS score changed 7 d after treatment;;The incidence of asymptomatic intracranial hemorrhage within 48h;The incidence of non-intracranial hemorrhage within 7 days;thrombocytopenia within 7d; | — |
Countries
China
Contacts
Public ContactYongpeng Yu
The Affiliated Weihai Central Hospital of Qingdao University
Outcome results
None listed