Effect of perioperative intravenous esmolol and lidocaine infusion on postoperative rapid recovery in patients undergoing Thyroid surgery: a randomized controlled trial

Status

Recruiting

Phases

Phase 4

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR1900025923

Enrollment

Unknown

Registered

2019-09-14

Start date

2019-09-15

Completion date

Unknown

Last updated

2019-09-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Thyroid Surgery

Interventions

Lidocaine group:Lidocaine

Esmolol group:Esmolol

Saline control group:Normal saline

Eligibility

Sex/Gender

All

Age

18 Years to 65 Years

Inclusion criteria

Inclusion criteria: ASA I-II, patients aged 18-65 years undergoing elective Thyroid surgery (including total thyroidectomy, subtotal thyroidectomy, radical thyroidectomy), Sign informed consent.

Exclusion criteria

Exclusion criteria: Contraindication of beta-blocker administration; Suffering from endocrine and metabolic diseases and nervous system diseases; Patients with severe liver, kidney and cardiopulmonary diseases; Bradycardia, asperger's syndrome, preexcitation syndrome, severe atrioventricular block; Long-term use of painkillers or cortisol drugs; Previous history of alcohol addiction.

Design outcomes

Primary

Measure	Time frame
QoR-40;	—

Secondary

Measure	Time frame
Sufentanil and Remifentanil consumption ;Extubation time;Visual Analogue Scale (VAS) ;	—

Countries

China

Contacts

Public ContactChenglan Xie

The Affiliated Huaian Hospital of Xuzhou Medical University, Huai'an Second Hospital

xiechenglan@163.com+86 13776701556

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026