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Renal blood flow resistance index predicting the value of acute kidney injury induced by septic shock: a diagnostic test

Renal blood flow resistance index predicting the value of acute kidney injury induced by septic shock: a diagnostic test

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR1900025921
Enrollment
Unknown
Registered
2019-09-14
Start date
2019-09-23
Completion date
Unknown
Last updated
2019-09-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

sepsis, acute kidney injury

Interventions

Gold Standard:Acute kidney injury KDIGO standard.
Index test:Renal&#32
blood&#32
flow&#32

Sponsors

Shenzhen Second People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1. Age, gender: 18-75 years old, male or female; 2. septic shock: On the basis of sepsis, after adequate fluid resuscitation, sustained hypotension requires maintenance of vasoactive drugs, mean arterial pressure (MAP)>= 65 mmHg and Lactate >=2.0 mmol/L; 3. Sign the informed consent form.

Exclusion criteria

Exclusion criteria: 1. Combined with chronic kidney disease; 2. Combined with other causes of shock, such as acute myocardial infarction, cerebral infarction or cerebral hemorrhage; 3. The presence of intra-abdominal hypertension (Grade IV: intra-abdominal pressure > 25 mmHg), renal artery stenosis or the use of non-steroidal anti-inflammatory drugs (NSAIDs) and other factors affecting renal blood flow; 4. Patients who are expected to die within 48 hours in the ICU; 5. Pregnancy; 6. Patients who are considered to be unsuitable for the purpose of this trial.

Design outcomes

Primary

MeasureTime frame
Renal blood flow resistance index;SEN, SPE, ACC, AUC of ROC;

Countries

China

Contacts

Public ContactWu Ming

Shenzhen Second People's Hospital

Boshiyy@126.com+86 15814468590

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026