sepsis, acute kidney injury
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Age, gender: 18-75 years old, male or female; 2. septic shock: On the basis of sepsis, after adequate fluid resuscitation, sustained hypotension requires maintenance of vasoactive drugs, mean arterial pressure (MAP)>= 65 mmHg and Lactate >=2.0 mmol/L; 3. Sign the informed consent form.
Exclusion criteria
Exclusion criteria: 1. Combined with chronic kidney disease; 2. Combined with other causes of shock, such as acute myocardial infarction, cerebral infarction or cerebral hemorrhage; 3. The presence of intra-abdominal hypertension (Grade IV: intra-abdominal pressure > 25 mmHg), renal artery stenosis or the use of non-steroidal anti-inflammatory drugs (NSAIDs) and other factors affecting renal blood flow; 4. Patients who are expected to die within 48 hours in the ICU; 5. Pregnancy; 6. Patients who are considered to be unsuitable for the purpose of this trial.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Renal blood flow resistance index;SEN, SPE, ACC, AUC of ROC; | — |
Countries
China
Contacts
Shenzhen Second People's Hospital