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A Multicenter, Randomized, Controlled Trial for Benign and Malignant Pleural Effusion Diagnosed by Flexible Thoracoscopy with Hybrid Knife

A Multicenter Randomized Controlled Trial for Benign and Malignant Pleural Effusion Diagnosed by Flexible Thoracoscopy with Hybrid Knife

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR1900025885
Enrollment
Unknown
Registered
2019-09-12
Start date
2018-10-01
Completion date
Unknown
Last updated
2019-09-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Benign and Malignant Pleural Effusion

Interventions

HBK Group:Pleural biopsy with Hybrid Knife
RF Group:Pleural biopsy with Routine biopsy forceps

Sponsors

The First Hospital of China Medical University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Patients with pleural effusion of unknown origin (patients with pleural effusion aspiration and/or negative biopsy); 2. Sign the informed consent; 3. Patients should have chest CT, biochemical examination of pleural effusion and cytological examination of pleural effusion before surgery.

Exclusion criteria

Exclusion criteria: 1. Cytological examination of pleural effusion suggests "highly suspected" patients (unless the results of cytological examination are inconsistent with clinical manifestations and CT findings); 2. The pleural nodules or masses were visible on CT; 3. Pleural nodules or masses are visible during thoracoscopy; 4. Thoracoscopy is not available for severe pleural adhesions; 5. Severe cardiopulmonary dysfunction and intolerance to thoracoscopic treatment; 6. Coagulation dysfunction.

Design outcomes

Primary

MeasureTime frame
diagnostic yield;operation time;specimen size;—

Secondary

MeasureTime frame
perioperative complication rate;extubation time;—

Countries

China

Contacts

Public ContactGang Hou

The First Hospital of China Medical University

hougangcmu@163.com+86 13840065481

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026