postoperative pulmonary complications
Conditions
Interventions
PCV-VG group:Pressure control-volume assurance ventilation during operation
Sponsors
West China Hospital, Sichuan University
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Aged >= 18 years; 2. ASA classification I-III; 3. Planned abdominal surgery >= 2 hours; 4. Undergoing abdominal surgery and general anaesthesia expected to be extubated; 5. With an intermediate-to-high risk for postoperative pulmonary complications (as defined by the ARISCAT score>=26); 6. Written inform consent.
Exclusion criteria
Exclusion criteria: 1. Refused to cooperate or be inappropriate; 2. Requiring re-operation or postoperative ventilation/circulation supports; 3. Acute lung injury or acute respiratory distress syndrome in last three months; 4. With cardiac insufficiency (NYHA >= 3), previous cerebral infarction history, severe liver disease (such as liver failure) or chronic renal failure (glomerular filtration rate 30 kg/m; 6. Participation in another experimental protocol at the time of intervention selection.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Postoperative pulmonary complications, including respiratory failure, respiratory infection (pneumonia), pleural effusion, atelectasis, pneumothorax, bronchospasm, aspiration pneumonitis;Lung compliance; | — |
Secondary
| Measure | Time frame |
|---|---|
| the severity grade of postoperative pulmonary complications;Postoperative pulmonary complications, including respiratory failure, respiratory infection (pneumonia), pleural effusion, atelectasis, pneumothorax, bronchospasm, aspiration pneumonitis;Postoperative reintubation;Postoperative non-planed transferred to ICU;Postoperative nausea and vomiting;Postoperative mortality;Length of Hospital Stay;Arterial oxygen saturation (SpO2);Driving pressure; | — |
Countries
China
Contacts
Public ContactHai Yu
West China Hospital, Sichuan University
Outcome results
None listed