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Comparison of efficacy and prognosis of different treatment regimens for advanced hypopharyngeal carcinoma: a multicenter prospective real-world study

Comparison of efficacy and prognosis of different treatment regimens for advanced hypopharyngeal carcinoma: a multicenter prospective real-world study

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR1900025877
Enrollment
Unknown
Registered
2019-09-12
Start date
2019-09-11
Completion date
Unknown
Last updated
2019-09-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hypopharyngeal cancer

Interventions

1:Surgery-based comprehensive treatment
2:Non-surgical treatment

Sponsors

Nanfang Hospital of Southern Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1) Patients with advanced diagnosis of hypopharyngeal carcinoma (clinical stage III, IVa and IVb); 2) Pathological diagnosis of hypopharyngeal squamous cell carcinoma; 3) Male or non-pregnant women aged >= 18 years; 4) The ECOG score is 0~2 points, and the expected survival is greater than 3 months; 5) HGB>=80g/L, WBC>=3x10^9/L, PLT>=70x10^9/L, heart, lung, liver and kidney coagulation function; 6) Patients and their families agree and sign an informed consent form.

Exclusion criteria

Exclusion criteria: 1) Those who have had other tumor history or merged with the second tumor at the same time; 2) Those who have a history of immunotargeting therapy or have a history of related drug allergies; 3) At the same time suffering from other uncontrolled serious diseases, or abnormal organs of vital organs; 4) Women are pregnant or breastfeeding; 5) Those who have psychological or mental factors leading to no normal civil behavior or uninformed consent; 6) Drug and/or alcohol abuse or other circumstances that the investigator considers inappropriate.

Design outcomes

Primary

MeasureTime frame
PFS;

Secondary

MeasureTime frame
ORR;OS;Quality of Life;

Countries

China

Contacts

Public ContactXiangping Li

Department of Otolaryngology, Nanfang Hospital, Southern Medical University

li321162@qq.com+86 13602705825

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026