Dyslipidemia
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Non-spleen deficiency turbid non-hyperlipidemia group inclusion criteria: 1. Non-dyslipidemia: Adult fasting 12 hours serum TC 1.0 mmol/L (40 mg/dl); 2. TCM diagnosis did not reach the diagnostic criteria for spleen deficiency, phlegm and spleen deficiency syndrome; 3. Aged 18 to 75 years old; 4. Volunteer to participate in the trial and sign the informed consent form. Dyslipidemia patients enrolled in the standard1 Western medicine meets the diagnostic criteria for dyslipidemia: 1. Adult fasting 12 hours serum TC >=5.2mmol/L (200mg/dl) or TG >=1.7mmol/L (150mg/dl), or LDL-C >=3.4 mmol/L (130mg / dl Or HDL-C <1.0 mmol/L (40 mg/dl). TC is a mandatory item; 2. medical history for more than three months; 3. Chinese medicine meets the diagnostic criteria of spleen-qi deficiency syndrome or spleen deficiency and phlegm syndrome; 4. Aged 18 to 75 years old; 5. Volunteer to participate in the trial and sign the informed consent form.
Exclusion criteria
Exclusion criteria: 1. Subjects with acute myocardial infarction, cerebrovascular accident, severe trauma or major surgery within six months; 2. Secondary hyperlipidemia: Hyperlipidemia caused by nephrotic syndrome, hypothyroidism, gout, acute or chronic hepatobiliary diseases, and diabetes; 3. Family hereditary dyslipidemia; 4. Hyperlipidemia caused by drugs (phenothiazines, beta-blockers, adrenocortical steroids and certain contraceptives, etc.); 5. Heparin, thyroxine therapeutics, and other subjects who are affecting lipid metabolism drugs are being used; 6. Take antibiotics within 2 months before sampling, take microbial live bacteria preparations (including yogurt) within 1 week before sampling, and take statin lipid-lowering drugs 2 weeks before sampling; 7. Consolidation of subjects with severe primary diseases such as liver, kidney, and hematopoietic system.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Intestinal flora;Blood lipid;Intestinal flora pathway protein; | — |
Secondary
| Measure | Time frame |
|---|---|
| Lipid metabolism related protein; | — |
Countries
China
Contacts
The Affiliated Hospital of Liaoning University of Traditional Chinese Medicine