sever hepatitis B (liver failure)
Conditions
Interventions
Nutrition intervention group:nutritional intervention
Control:Nutrition intake according to one's own wishes
Sponsors
The First Affiliated Hospital of Medical College, Zhejiang University
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1) The patient agrees to participate in the study and sign the informed consent. 2) Unlimited sex, aged 18-65 years; 3) HBsAg positive lasted for more than 6 months and HBV-DNA positive (higher than 200 IU/ml); 4) Extreme fatigue and severe gastrointestinal symptoms such as anorexia, abdominal distension, nausea and vomiting. 5) Progressive deepening of jaundice in a short period of time (serum total bilirubin is 10 times higher than the upper limit of normal value or increases daily by more than 17.1 umol/L); 6) The tendency of bleeding was obvious, PTA was less than 40%, and other causes were excluded.
Exclusion criteria
Exclusion criteria: 1) Acute fatty liver of pregnancy; 2) Drug-induced liver injury; 3) Alcoholic liver disease (drinking more than 20 g per day for women, 40 g for men and more than 5 years); 4) Autoimmune liver disease; 5) Congenital metabolic liver diseases, such as Wilson's disease, hemochromatosis, etc.; 6) Severe hepatitis caused by hepatitis B recurrence after transplantation; 7) Patients with other viral infections were positive for anti-HAV IgM, anti-HCV, anti-HEV IgM, anti-HEV-IgG, anti-HDV-IgM and anti-HIV antibodies. 8) Complicated with serious underlying diseases, including uncontrolled clinically significant heart, lung, kidney, digestion, nerve, mental disorders, immune diseases, metabolic diseases, malignant tumors, etc.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Body Composition Analysis;liver function;Daily total energy intake;????????; | — |
Countries
China
Contacts
Public ContactHuang Jianrong
The First Affiliated Hospital of Medical College, Zhejiang University
Outcome results
None listed