Blastocyst formation
Conditions
Interventions
Gold Standard:The blastocyst formation standard is based on the Istanbul consensus workshop on embryo assessment.
Index test:zygotic 
paramters 
(ZMPs)
Sponsors
Assisted Reproductive Technology Unit, Department of Obstetrics and Gynaecology, Faculty of Medicine, The Chinese University of Hong Kong
Eligibility
Sex/Gender
Female
Age
22 Years to 48 Years
Inclusion criteria
Inclusion criteria: Patients eligible for inclusion are 1. consecutive women underwent IVF treatment; 2. the treatment cycle has oocytes for time-lapse incubation, and 3. they are planned for extended culture before oocyte retrieval. All the subjects will be evaluated and screen for study eligibility by the principal investigator prior to study entry.
Exclusion criteria
Exclusion criteria: Patients with more than half of the zygotes that are not able to record the ZMPs accurately will be excluded. If a zygote is transferred or cryopreserved before day 5, it will be considered as an incorrectly measured zygote. In our pilot data, 30% of the zygotes cannot be measured correctly due to their blur imaging, obstructions on the boundary or its degeneration.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Blastocyst formation; | — |
Secondary
| Measure | Time frame |
|---|---|
| Ongoing pregnancy;Live birth rate;Fertlization rate;Available embryo rate; | — |
Contacts
Public ContactLi Tin Chiu
Assisted Reproductive Technology Unit, Department of Obstetrics and Gynaecology, Faculty of Medicine, The Chinese University of Hong Kong
Outcome results
None listed