Abnormal fetal ultrasound structure
Conditions
Interventions
Nervous system malformation, skeletal malformation, digestive system malformation, cardiovascular system, urinary system, craniofacial malformation and control group:None
Sponsors
Wuhan Children's Hospital
Eligibility
Sex/Gender
Female
Inclusion criteria
Inclusion criteria: Fetal structural malformation was detected in prenatal ultrasound examination and/or magnetic resonance imaging in our hospital, or was referred to our hospital for ultrasound examination and/or magnetic resonance imaging to confirm the diagnosis.Abnormalities include structural deformity, translucent thickness of neck >=3.5mm and cystic edema.
Exclusion criteria
Exclusion criteria: Isolated ultrasound soft markers, such as choroid plexus cyst, echogenic lesions in the heart or intestine, thickened neck folds, lack of nasal bone, single umbilical artery, or persistent right umbilical vein. Fetal samples will be collected using chorionic villus sampling, amniocentesis, and umbilical cord biopsy, depending on gestational age at the time of invasive prenatal testing.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| CMA, WES; | — |
Countries
China
Contacts
Public ContactHe XueLian
Wuhan Children's Hospital, Tongji Medical College, Huazhong University of Science and Technology
Outcome results
None listed