clinical anesthesia
Conditions
Interventions
group 2:dexmedetomidine 0.5ug/kg
group 3:lidocaine+dexmedetomidine 0.5ug/kg
group 4:control
Sponsors
Shiyan People's Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: The American Society of Anesthesiologists (ASA) physical status I and II; aged between 18 to 60 years; BMI 18-25 kg/m2; Patients undergoing elective thyroidectomy in general anesthesia.
Exclusion criteria
Exclusion criteria: 1. Patients with heart, brain, lung, liver, kidney and other major organ diseases; 2. Allergic to dexmedetomidine, lidocaine and other experimental drugs; 3. Recent users of beta blockers and alpha 2 agonists; 4. Alcohol and drug abusers; 5. Long-term users of sedatives, analgesics and long-term alcoholics; 6. Patients with a history of mental illness, language communication disorder and inability to understand the experiment content.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| cytokines; | — |
Secondary
| Measure | Time frame |
|---|---|
| Consumption of propofol;postoperative pain;Postoperative recovery quality;patient satisfaction;Postoperative incidence of nausea and vomiting;Postoperative intestinal function recovery time; | — |
Countries
China
Contacts
Public ContactRan Ran
Shiyan people's hospital affiliated to Hubei University of Medicine
Outcome results
None listed