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Detection of MRGPRX2 receptor expression in peripheral blood by double antibody sandwich ELISA and its clinical application in the diagnosis of chronic urticaria

Detection of MRGPRX2 receptor expression in peripheral blood by double antibody sandwich ELISA and its clinical application in the diagnosis of chronic urticaria

Status
Recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR1900025723
Enrollment
Unknown
Registered
2019-09-06
Start date
2019-09-03
Completion date
Unknown
Last updated
2019-09-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

chronic urticaria

Interventions

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Sponsors

Xi'an Jiaotong University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
6 Years to 80 Years

Inclusion criteria

Inclusion criteria: Case group: 1. Age ranges from 6 to 80 years old; 2. Patients have no other disease in the near future; 3. Patients are diagnosed as chronic urticaria (The course of the disease is greater than or equal to 6 weeks); 4. Patients volunteere to participate in this project and be able to practitioners as required; 5. Patients have signed informed consent form, and be able to complete as required. Control group: 1. Healthy people. 2. No history of chronic urticaria; 3. There is no history of the family of chronic urticaria; 4. No disease in the near future.

Exclusion criteria

Exclusion criteria: 1. The patients of chronic urticaria have other disease; 2. Patients have indications of acute infection; 3. Patients have been diagnosed with physical urticaria (including artificial urticaria), cholinergic urticaria or urticaria vasculitis; 4. The patients are unable to cooperation or do not adhere to treatment or are judged poor adherence; 5. Pregnant women and nursing mothers; 6. Patients are joining in other clinical trials.

Design outcomes

Primary

MeasureTime frame
accuracy rate;Positive predictive value;Negative predictive value;

Countries

China

Contacts

Public ContactLangchong He

Xi'an Jiaotong University

helc@mail.xjtu.edu.cn+86 029 82655392

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026