National natural youth supporting fund and self-raised
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: (1) Aged >= 18 years old, acute dyspnea with hypoxemia and dyspnea (without oxygen, respiratory frequency =24 times/min, pulse oximetry <= 94%); (2) no obvious oropharyngeal active bleeding, no obvious obstruction of sputum discharge; (3) consciousness; (4) the subjects voluntarily participate in the study and have signed the informed consent;
Exclusion criteria
Exclusion criteria: (1) The presence of invasive ventilation indications, must be intubated as soon as possible and invasive ventilator assisted breathing standards; (2) Patients with hemodynamic instability after active fluid resuscitation and vasoactive drugs (systolic blood pressure <90 mmHg, mean arterial pressure <50 mmHg); (3) The Glasgow coma scale is below 13; (4) Refuse to cooperate with active treatment or refuse to participate in this study; (5) Unable to remove respiratory secretions; (6) Malignant tumor history and significantly affect the prognosis; (7) Severe ventricular arrhythmias or myocardial ischemia; (8) There is active bleeding in oropharynx, head, face, airway and chest and abdomen, which has not yet been corrected.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| respiratory rate;arterial partial pressure of oxygen; | — |
Secondary
| Measure | Time frame |
|---|---|
| hospital stays;Rate of endotracheal intubation during hospitalization; | — |
Countries
China
Contacts
The First Affiliated Hospital of Zhengzhou University