Localized scleroderma
Conditions
Interventions
1:simple fat transplantation
2:fat transplantation + adipose stem cells
3:fat transplantation + vascular matrix components SVF
Sponsors
Peking Union Medical College Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 50 Years
Inclusion criteria
Inclusion criteria: (1) patients with localized scleroderma diagnosed by dermatology; (2) localized scleroderma is in stable phase; (3) localized scleroderma causes facial depression; (4) aged 18-50 years; (5) subject or legal representative informed consent, volunteered to test, and signed informed consent.
Exclusion criteria
Exclusion criteria: (1) patients undergoing hormone, anti-fibrotic and anti-scarring treatment; (2) patients with unstable or advanced stage of scleroderma; (3) pregnant, pregnant or lactating subjects; (4) participating in other clinical trials or participating in other clinical trials within 3 months; (5) there are other basic diseases such as cardiovascular and cerebrovascular diseases. (6) the patient or legal representative refuses to participate in the study, or the patient cannot cooperate with the trial-related content due to various reasons such as mental, cognitive, and language.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Appearance rating;Facial volume measurement;Facial blood flow measurement; | — |
Countries
China
Contacts
Public ContactChunhua Zhao
Jimo District Qingdao Hospital of Traditional Chinese Medicine
Outcome results
None listed