A randomized, double-blind clinical study for the effect of preoperative butorphanol on anaesthesia related complications in patients

Status

Recruiting

Phases

Phase 4

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR1900025705

Enrollment

Unknown

Registered

2019-09-06

Start date

2019-08-30

Completion date

Unknown

Last updated

2019-09-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

anesthesia related complication

Interventions

contrast group:normal saline (NS)

butorphanol group 1:butorphanol 0.02mg/kg

butorphanol group 2:butorphanol 0.03mg/kg

Eligibility

Sex/Gender

Male

Inclusion criteria

Inclusion criteria: 1) Aged from 30 to 75 years, regardless of gender; 2) 18kg/m2 <= BMI <= 28kg/m2; 3) ASA score levels I to II; 4) General surgery or general anesthesia in thoracic surgery; 5) Clearly understand, voluntarily participate in the study, and sign the informed consent.

Exclusion criteria

Exclusion criteria: 1) Pregnant or lactating women; 2) Allergic to butorphanol and other opioids; 3) Opioid dependence or opioid tolerance; 4) Preoperative cognitive dysfunction; 5) Abnormal liver and kidney function; 6) Abnormal electrolyte; 7) The investigators do not consider it appropriate to participate in this clinical trial.

Design outcomes

Primary

Measure	Time frame
Emergence agitation;	—

Secondary

Measure	Time frame
nausea and vomiting;	—

Countries

China

Contacts

Public ContactJianbo Wu

Department of Anesthesiology, Qilu Hospital of Shandong University

jianbowu@126.com+86 13805319310

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 10, 2026