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A cohort study for the effects of low-dose X-ray on blood immune cell damage in patients undergoing interventional therapy

A cohort study for the effects of low-dose X-ray on blood immune cell damage in patients undergoing interventional therapy

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR1900025682
Enrollment
Unknown
Registered
2019-09-05
Start date
2019-10-20
Completion date
Unknown
Last updated
2019-09-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Immunocyte damage

Interventions

Dose groups of ? 0.1Gy, 0.1-0.3Gy, ? 0.3Gy:N/A

Sponsors

Zhujiang Hospital, Southern Medical University.
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: (1) Aged 18-80 years, gender is not limited; (2) Patients who need to accept interventional therapy; (3) Voluntary participation in the clinical trial, understanding and signing the informed consent;

Exclusion criteria

Exclusion criteria: (1) Those who plan to undergo interventional therapy again and continue to receive radiation therapy; (2) Comply with severe cardiovascular, liver, blood system,neuroendocrine system diseases, Alanine aminotransferase and alkaline phosphatase 1.5 times highter than normal value, serum creatinine > 2 mg/dl (194.5 umol/L), serum potassium > 5.5 mol/L; cancer patients;psychiatric patients; (3) Persons with genetic or DNA repair syndrome or family history of disease; (4) Persons previously exposed to medical/occupational radiation; (5) Pregnant or pregnant women and lactating women; (6) Allergic constitution, or known drug allergy; (7) Patients with cancer or immunodeficiency diseases, leukocyte and lymphocyte abnormalities; (8) Participate in other drug clinical trial within one month; (9) Patients who can not complete the study or comply with the requirements of the study (due to management reasons or other reasons) according to the judgement of the researchers.

Design outcomes

Primary

MeasureTime frame
Lymphocyte micronucleus rate;Lymphocyte aberration rate;

Secondary

MeasureTime frame
Tumors or immune system diseases occured;

Countries

China

Contacts

Public ContactFu Xiaohua

Zhujiang Hospital, Southern Medical University.

fuxiaohua1976@126.com+86 13556149752

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026