intracranial tumor surgery
Conditions
Interventions
C group:VT set at 8ml/kg of ideal body weight
P group:VT will be set at 6 ml/kg of ideal body weight combined with individualized PEEP (PEEPx) during intraoperative dura mater opening
Sponsors
The Second Affiliated Hospital of Soochow University
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Patients scheduled to receive elective intracranial primary intra-axial tumor resection who are younger than 65 years and elder than 18 years; 2. The maximum diameter of the tumor is 2~5 cm; 3. ASA class for I-II; 4. 18.5 < BMI < 28; 5. Glasgow Coma Scale score of more than 8 points.
Exclusion criteria
Exclusion criteria: 1. Patients with chronic lung diseasepulmonary infection and other severe pulmonary complications such as acute respiratory failure; 2. Patients with a history of pulmonary surgery; 3. Patients with severe brain, heart, liver and kidney diseases; 4. Patients with nerve injury affecting breathing preoperative; 5. Pregnant women; 6. Refuse to participate in the researcher.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| rSO2; | — |
Secondary
| Measure | Time frame |
|---|---|
| Partial pressure of oxygen in arterial blood;Partial pressure of carbon dioxide in arterial blood;Oxygenation index in arterial blood;Lactic acid level in arterial blood;Mean arterial pressure;Pulmonary ultrasound scores; | — |
Countries
China
Contacts
Public ContactHairui Liu
The Second Affiliated Hospital of Soochow University
Outcome results
None listed