Recurrent aphthous stomatitis
Conditions
Interventions
Intervention group:Total glucosides of paeony capsules
Sponsors
Peking University Hospital of Stomatology
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: (1) History of 1 year or more; (2) In the past six months, ulcers have happened twice a month or more; (3) The number of ulcers every period is 1 or more; (4) The type of recurrent oral ulcer is light; (5) Aged 18-80 years; (6) Those who did not participate in any drug trial within 3 months prior to the election; (7) Understand the whole process of observation and study, and voluntarily participate in and sign the informed consent form.
Exclusion criteria
Exclusion criteria: (1) Behcet's disease; (2) Systemic diseases background: anemia, immunodeficiency diseases, autoimmune diseases, malignant tumors, severe cardiovascular and cerebrovascular diseases (such as patients with myocardial infarction undergoing coronary stent implantation); (3) Use analgesics within 24 hours, use antibiotics and anti-inflammatory drugs within 1 month, use corticosteroids and immunologic preparations within 3 months; (4) Those who have long-term diarrhea for various reasons; (5) Patients with mental disorders and other patients with poor compliance and difficulty in cooperating; (6) Female patients are pregnant, lactating or planning a pregnancy during the study period; (7) Clinically significant abnormalities (including physical examination and laboratory examination) appear during screening, and the investigator believes that the abnormality will affect the patient's safety completion of the study, such as the critical value of laboratory tests.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| interval, I;number, N; | — |
Secondary
| Measure | Time frame |
|---|---|
| The degree of pain;Area;Quality of life; | — |
Countries
China
Contacts
Public ContactLiu Hongwei
Peking University Hospital of Stomatology
Outcome results
None listed