AIDS
Conditions
Interventions
DTG Group:Use the ART program with DTG
non-DTG group:Use an ART solution that does not contain DTG
Sponsors
Zhengzhou Sixth People's Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: (1) Male and female aged 18-65 years; (2) HIV antibody confirmation test is positive; (3) Those who have not received anti-HIV treatment and have opportunistic infections; (4) HIV viral load >=1000 copies/mL; (5) Those who have no recent birth plans and who agree to take effective non-pharmaceutical contraceptives during the trial period and within 3 months after the end of dosing; (6) According to clinical judgment, the ART regimen containing the integrase inhibitor DTG or other ART regimen without integrase inhibitor can be used; (7) Subjects should fully understand the purpose, nature, methods, and possible adverse reactions, and voluntarily participate in the trial and sign an informed consent form.
Exclusion criteria
Exclusion criteria: (1) Patients who have received anti-HIV treatment; (2) HIV RNA <500 copies/ml; (3) Pregnant women or women of childbearing age have a pregnancy plan; (4) patients with tumors; (5) Poor medication compliance (if it is not possible to take medication according to doctor's advice and can not return to follow the time node); (6) Patients with a mental illness or a previous history of mental illness; (7) suspect or determine the history of alcohol and drug abuse; (8) Those who have entered other clinical trials in the past 3 months; (9) Other factors that the investigator believes are not suitable for inclusion.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Lymphocyte subset;HIV-1 viral load; | — |
Secondary
| Measure | Time frame |
|---|---|
| IL-6;Blood routine;CRP; | — |
Countries
China
Contacts
Public ContactZhao Qingxia
Zhengzhou Sixth People's Hospital
Outcome results
None listed