Pulmonary Arterial Hypertension Associated with Portal Hypertension
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Aged 16-75 years; 2. Clinically diagnosed cirrhosis (by biopsy, imaging examination or clinical manifestation); 3. Obtain informed consent.
Exclusion criteria
Exclusion criteria: 1. Common contraindications for HVPG or right heart catheterizaiton (allergy to contrast, severe infection); 2. Diagnosed malignancies; 3. History or plan of TIPS, liver transplantation, and devascularization of blood vessels after spleen resection; 4. Non-cirrhotic portal hypertension; 5. Portal vein thrombosis or cavernous transformation of portal vein; 6. Pregnancy or lactation.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| mPAP;Description of the general epidemiology of the patient;Ultrasonic Cardiogram;arterial blood gas analysis;hepatic venous pressure gradient;WHO grading; | — |
Secondary
| Measure | Time frame |
|---|---|
| NT-pro BNP; | — |
Countries
China
Contacts
Shandong Provincial Hospital