Lung cancer
Conditions
Interventions
Experimental group :Drug-loaded microsphere embolization chemotherapy
control group :Guànzhù huàliáo 4/5000 Infusion chemotherapy
Sponsors
Shandong Institute of Medical Imaging
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Aged >=18 years old, male or female; 2. Diagnosis of lung cancer by gastroscopy or biopsy of histology; 3. Patients with intermediate or advanced stage who have lost their chance of surgery or who cannot tolerate surgery; 4. The patient's survival is expected to exceed 3 months; 5. ECOG =3.0x10^9/L, NE>=1.5x10^9/L, Hgb>=10.0g/L, PLT>=100x10^9/L, ALT, AST and bilirubin levels <=1.5 times the upper limit of normal, coagulation function is normal, blood CREA <=1.5 times the upper limit of normal, BUN is normal; 7. Cardiopulmonary function is basically normal; 8. Subjects volunteered to join the study, signed informed consent, and were well-adhered to follow-up.
Exclusion criteria
Exclusion criteria: 1. There are contraindications for general endovascular treatment and contrast agent application; 2. Patients with cachexia or heart, lung, liver and kidney failure; 3. Patients with severe infections and chemotherapy contraindications with severe reduction of white blood cells and platelets; 4. Patients with severe bleeding tendency and iodine allergy and other angiographic contraindications; 5. The bronchial artery and the spinal cord artery coexist or coincide with the traffic is a relative contraindication. 6. Patients with other malignancies within 5 years; 7. Patients with a history of psychotropic substance abuse who are unable to quit or have a mental disorder; 8. Patients who have participated in other drug clinical trials within 4 weeks; 9. According to the investigator's judgment, there are serious patients who are at risk to the patient's safety or affect the patient's accompanying disease to complete the study; 10. The investigator believes that it is not suitable for inclusion.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| PFS; | — |
Countries
China
Contacts
Public ContactJianqiang Shang
Shandong Institute of Medical Imaging
Outcome results
None listed