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Comparative study for the effect of variable speed and constant speed pump injection of norepinephrine in the prevention and treatment of spinal anesthesia-induced hypotension in cesarean delivery

Comparative study for the effect of variable speed and constant speed pump injection of norepinephrine in the prevention and treatment of spinal anesthesia-induced hypotension in cesarean delivery

Status
Recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR1900025585
Enrollment
Unknown
Registered
2019-09-02
Start date
2019-09-02
Completion date
Unknown
Last updated
2019-09-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cesarean delivery

Interventions

Group A:pump norepinephrine with fixed rate
Group B:pump norepinephrine with variable rate

Sponsors

Womens' Hospital, School of Medicine, Zhejiang University
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 40 Years

Inclusion criteria

Inclusion criteria: (1) Maternal women between the ages of 18 and 40 years; (2) Gestational weeks 37 t0 42 weeks (single pregnancy); (3) Sign informed consent.

Exclusion criteria

Exclusion criteria: (1) contraindications for spinal anesthesia; (2) non-selective surgery; (3) abnormal placenta previa or other placenta; (4) fetal abnormalities; (5) hypertension in the past or pregnancy; (6) associated with cardiovascular, respiratory, kidney and other organ diseases; (7) thrombocytopenia; (8) weight 100 kg; (9) height 180 cm.

Design outcomes

Primary

MeasureTime frame
The incidence of hypotension;Number of interventions;Dosage of vasoactive drugs;

Secondary

MeasureTime frame
Maternal outcomes (Nausea and Vomiting; Bradycardia; Tachycardia; Hypertension; Dizzy; Dyspnea);

Countries

China

Contacts

Public ContactXiaowei Qian

Womens' Hospital, School of Medicine, Zhejiang University

qianxw@zju.edu.cn+86 15700157161

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026