coronary heart disease
Conditions
Interventions
Case Series:N/A
Sponsors
Zhongda Hospital of Southestern University
Eligibility
Sex/Gender
Male
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Voluntarily participate in this study and sign the informed consent; 2. Male or female in non-gestational response with age greater than or equal to 18 years and less than or equal to 80 years; 3. Coronary angiography showed that the stenosis degree of the proximal and middle segments of coronary arteries was between 50% and 75% meeting all the above criteria.
Exclusion criteria
Exclusion criteria: 1. Previous coronary artery bypass grafting; 2. Severe angular lesions (>60 degrees);Lesions with prominent intimal laceration; 3. Severe reduced left cardiac function (EF<40%); 4. Severe liver and kidney diseases (liver dysfunction and non-cardiac diseases cause AST/ALT over 3 times the upper limit of normal value;Cirrhosis;GFR < 60 ml/min / 1.73 m2); 5. Uncontrolled moderate to severe hypertension (systolic blood pressure is still more than 160mmHg or diastolic blood pressure is more than 100mmHg after regular antihypertensive treatment); 6. Life-threatening arrhythmia or hemodynamic instability or cardiogenic shock; 7. Coagulation dysfunction or significant bleeding tendency (e.g. allergy, active bleeding, previous history of intracranial bleeding, gastrointestinal bleeding within 6 months and operation within 30 days); 8. Patients with ischemic stroke within one week; 9. Bronchial asthma, chronic obstructive pulmonary disease (COPD) and other patients with severe dyspnea; 10. Any of the following laboratory tests exist: platelets less than 100*109/L,Hb<100g/L; 11. 30 days to participate in another trial drug or medical device study; 12. Researchers and/or immediate family members involved in the study; 13. Patients with other serious diseases whose life expectancy is less than half a year; 14. Presence of pathological sinus syndrome, grade II or III atrioventricular block, or suspected syncope due to bradycardia; 15. Women who are pregnant or breast-feeding or who plan to become pregnant within one year; 16. The researcher believed that the patient had other conditions that were not suitable for participating in this study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| plaque characteristics;cardiovascular events;Lp-PLA2, Hs-CRP; | — |
Countries
China
Contacts
Public ContactTang Chengchun
Zhongda Hospital of Southestern University
Outcome results
None listed