Health effects investigation of plateau environment on resident and short-stay populations

Status

Recruiting

Phases

Early Phase 1

Study type

Observational

Source

ChiCTR

Registry ID

ChiCTR1900025542

Enrollment

Unknown

Registered

2019-08-31

Start date

2019-09-01

Completion date

Unknown

Last updated

2019-09-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Resident populations group+ Short-lived populations group:N/A

Eligibility

Sex/Gender

All

Age

18 Years to 60 Years

Inclusion criteria

Inclusion criteria: 1. Resident populations: (1) Age ranging from 18 to 60 years; (2) Signing informed consent; (3) Continuous residence in plateau area for 5 years or more; (4) No smoking history or smoking cessation for more than one year. 2. Short-lived populations: (1) Age ranging from 18 to 60 years; (2) Signing informed consent; (3) Continuous residence in plateau area for one month or more; (4) No smoking history or smoking cessation for more than one year.

Exclusion criteria

Exclusion criteria: 1. Resident populations: (1) Suffering from serious chronic diseases, such as heart disease, chronic obstructive pulmonary disease, etc. (2) Having undergone major operations (such as orthopaedics, cardiopulmonary, gastrointestinal and other operations) within half a year. 2. Short-lived populations: (1) Suffering from serious chronic diseases, such as heart disease, chronic obstructive pulmonary disease, etc. (2) Having undergone major operations (such as orthopaedics, cardiopulmonary, gastrointestinal and other operations) within half a year.

Design outcomes

Primary

Measure	Time frame
Black carbon;PM2.5;CO;NOx;SO2;O3;Fraction exhaled nitric oxide (FeNO);Malondialdehyde (MDA);Nitrite + nitrate;Cytokines such as IL-6, IFN?, TNFa;8-OHdG;P-Selectin/CD62P;Heart Rate Variability (HRV);Blood pressure;Blood cell count;Blood biochemistry;FEV1/FVC;Vascular elasticity index;Height;Weight;BMI;pH of exhaled condensate;Blood oxygen concentration;Lymphocyte subset immunophenotyping;Temperature;Relative humidity;Atmospheric pressure;Ultraviolet radiation intensity;Component analysis for drinking water;Exposure histology analysis of urine sample;Microbiological analysis of fecal sample;	—

Measure

Time frame

Black carbon;PM2.5;CO;NOx;SO2;O3;Fraction exhaled nitric oxide (FeNO);Malondialdehyde (MDA);Nitrite + nitrate;Cytokines such as IL-6, IFN?, TNFa;8-OHdG;P-Selectin/CD62P;Heart Rate Variability (HRV);Blood pressure;Blood cell count;Blood biochemistry;FEV1/FVC;Vascular elasticity index;Height;Weight;BMI;pH of exhaled condensate;Blood oxygen concentration;Lymphocyte subset immunophenotyping;Temperature;Relative humidity;Atmospheric pressure;Ultraviolet radiation intensity;Component analysis for drinking water;Exposure histology analysis of urine sample;Microbiological analysis of fecal sample;

—

Countries

China

Contacts

Public ContactJicheng Gong

College of Environmental Sciences and Engineering, Peking University

jicheng.gong@pku.edu.cn+86 18600923276

Outcome results