Mediastinal adenopathy
Conditions
Interventions
Gold Standard:endobronchial ultrasound-guided transbronchial needle aspiration.
Sponsors
The Second Affiliated Hospital of the Army Medical University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Aged >=15 years; 2. Patients with at least one mediastinal lesion with short-axis = 1 cm that is detected by thoracic image; 3. Patients with recently discovered mediastinal lesions, clinical respiratory symptoms of cough, expectoration, thoracalgia, apnea, or complicated lung lesions implicated by thoracic image, which indicates the need of biopsy to identify the etiology; 4. Patients should have undergone necessary preoperative laboratory examinations and other examinations such as cardiac ultrasound or CTA when necessary, in order to exclude potential contradictions; 5. Patients are informed and the consent form are acquired.
Exclusion criteria
Exclusion criteria: 1. Patients with contradictions to endoscopic examination, such as severe cardiopulmonary diseases, coagulation disorders, intolerance to anesthesia or endoscopic operation, psychiatric disorders, or severe neurosis, and so on; 2. The EBUS procedure fails to detect the mediastinal lesion; 3. The lesions are abundant in blood supply, close to large vessels, or other conditions detected by EBUS that indicates high risk to continue the biopsy; 4. The lesions are actually cysts or abscess; 5. Patients need for additional procedures other than EBUS examination (such as endobronchial biopsy); 6. Patients who have been involved in other clinical trials in the recent 3 months; 7. Patients have any other conditions that are considered to be inappropriate to be involved in this study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| diagnostic yield;diagnostic safety; | — |
Secondary
| Measure | Time frame |
|---|---|
| sample size;sample adequacy;operation time; | — |
Countries
Germany
Contacts
Public ContactYe Fan
Xinqiao Hospital
Outcome results
None listed