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Evaluation the Effectiveness of several toothpastes in preventing caries: a randomized control trial

Evaluation the Effectiveness of several toothpastes in preventing caries: a randomized control trial

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR1900025499
Enrollment
Unknown
Registered
2019-08-29
Start date
2019-09-01
Completion date
Unknown
Last updated
2019-09-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Dental caries

Interventions

Toothpaste Group 1 (Crest Defence Repair Toothpaste):Oral health education + Oral hygiene guidance
Toothpaste Group 2 ((Improved Crest Pearl Salt White Toothpaste):Oral health education + Oral hygiene guidance
Toothpaste group 3 (black girl fluoride-free toothpaste):Oral health education+Oral hygiene guidance

Sponsors

Department of Preventive Dentistry, School of Stomatology, Peking University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
3 Years to 5 Years

Inclusion criteria

Inclusion criteria: 1) Provide written informed consent before participation; 2) Agree not to participate in any other oral/dental product research during the study; 3) Agree to suspend the use of any non-study oral care products during the study; 4) Good health (ie, without any disease that may affect participation in the study), may participate in the study; 5) Daily oral cleaning using a manual toothbrush instead of an electric toothbrush 6) Being in the middle of kindergarten, aged between 3-5 years old; 7) Meet at least one of the following criteria: There are two to ten tooth surfaces with an ICDAS score greater than or equal to 3; or at least one tooth with an ICDAS score greater than or equal to 5; or Cariostat results indicate a high-risk susceptible group

Exclusion criteria

Exclusion criteria: 1) Failure to comply with research requirements; 2) Wearing an orthodontic appliance or tray, or having a plan for orthodontic treatment in the following year; 3) Any disease or condition that may affect the examination process or safely complete the study.

Design outcomes

Primary

MeasureTime frame
ICDAS score;

Secondary

MeasureTime frame
Cariostat value;

Countries

China

Contacts

Public ContactWensheng Rong

Department of Preventive Dentistry, School of Stomatology, Peking University

rongwensheng@vip.sina.com+86 13681354214

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026