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Clinical study for the pedicled intertrochanteric bone flap transfer in the treatment of avascular necrosis of the femoral head

Clinical study for the treatment of avascular necrosis of the femoral head with pedicled intertrochanteric bone flap transfer

Status
Recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR1900025494
Enrollment
Unknown
Registered
2019-08-29
Start date
2019-06-01
Completion date
Unknown
Last updated
2019-09-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Avascular necrosis of the femoral head

Interventions

Experimental Group:pedicled intertrochanteric bone flap transfer
Control Group:core decompression with impacted graft

Sponsors

Zhongshan Hospital of Fudan University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 50 Years

Inclusion criteria

Inclusion criteria: 1. Male and female aged between 18 to 50 years; 2. X-ray, CT, MRI or SPECT confirms the diagnosis of avascular necrosis of the femoral head and the ARCO stage is ARCO II, IIIA or IIIB(younger than 40); 3. The presence of hip joint symptoms like pain or limping; 4. Patient is willing to undergo the surgery; 5. Without other operative contraindications.

Exclusion criteria

Exclusion criteria: 1. Necrosis of the femoral head has progressed to collapsing stage with the area larger than 4mm (ARCO IIIC, IV); 2. SPECT indicated catabolic concentration at the necrotic focus; 3. Trauma or surgery history of the involved hip joint; 4. Combined with other diseases like osteoarthritis, developmental dysplasia of the hip (DDH) or rheumatoid arthritis; 5. Patient are willing to undergo regular surgical treatment; 6. Combined with other severe diseases; 7. Unable to finish the two-year follow-up.

Design outcomes

Primary

MeasureTime frame
Postoperative grafted bone survival rate;

Secondary

MeasureTime frame
Harris Hip Score;Postoperative femoral head collapsing rate;Femoral head renecrotic rate;

Countries

China

Contacts

Public ContactZuoqin Yan

Zhongshan Hospital of Fudan University

yan.zuoqin@zs-hospital.sh.cn+86 021-64041990-5488

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026