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A cases records based retrospective analysis of the relationship between TSH level and TPOAb status before 20 weeks gestation and maternal and infant outcomes

A cases records based retrospective analysis of the relationship between TSH level and TPOAb status before 20 weeks gestation and maternal and infant outcomes

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR1900025492
Enrollment
Unknown
Registered
2019-08-28
Start date
2019-09-01
Completion date
Unknown
Last updated
2019-09-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Subclinical hypothyroidism during pregnancy

Interventions

Case series:Nil

Sponsors

Zhujiang Hospital of Southern Medical University
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 48 Years

Inclusion criteria

Inclusion criteria: 1. 20 weeks before pregnancy in our hospital for the first prenatal examination, serum TSH FT4 TPOAb was determined; 2. TSH ranged from 0.1 to 10.0mIU/L, FT4 in the early trimester (0-13+6 weeks) ranged from 6.67 to 13.86pmol/L, and FT4 in the second trimester (14-27+6 weeks) ranged from 5.79 to 12.70 pmol/L.

Exclusion criteria

Exclusion criteria: 1. unnatural conception; 2. multiple pregnancy; 3. any medications (glucocorticoid antiepileptics or dopamine) that affect thyroid function during pregnancy; 4. has a history of thyroid disease or thyroid related surgery; 5. previous chronic diseases such as hypertension, diabetes or serious heart, liver and kidney diseases; 6. combined with other autoimmune diseases found before or during pregnancy; 7. incomplete clinical data.

Design outcomes

Primary

MeasureTime frame
TSH;FT4;TPOAb;—

Countries

China

Contacts

Public ContactPan Shilei

Zhujiang Hospital of Southern Medical University

1551402879@qq.com+86 15818149335

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026