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Ultrasound-guided quadratus lumborum block combined with local infiltration analgesia for postoperative analgesia in patients undergoing total hip arthroplasty: a randomized controlled trial

Ultrasound-guided quadratus lumborum block combined with local infiltration analgesia for postoperative analgesia in patients undergoing total hip arthroplasty: a randomized controlled trial

Status
Recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR1900025472
Enrollment
Unknown
Registered
2019-08-27
Start date
2020-01-15
Completion date
Unknown
Last updated
2020-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

osteoarthritis of the hip, osteonecrosis of the femoral head (Ficat IIIB or IV), and developmental dysplasia of the hip.

Interventions

C group:local infiltration analgesia
N group:quadratus lumborum block+local infiltration analgesia

Sponsors

Department of Anesthesiology, West China Hospital, Sichuan University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1) 18-80 years of age; 2) body mass index (BMI) of 20-35 kg/m2; 3) an American Society of Anesthesiologists (ASA) functional status of II-III; 4) primary unilateral total hip arthroplasty.

Exclusion criteria

Exclusion criteria: 1) hip ankylosis; 2) known allergy to the drugs used in this study; 3) a history of excessive opioid consumption; 4) a history of excessive alcohol consumption; 5) cognitive impairment; 6) psychiatric illness; 7) recognized neuromuscular disorder; 8) previous hip open surgery; 9) other neuropathic diseases of the hip on the target side; 10) inability to communicate verbally.

Design outcomes

Primary

MeasureTime frame
Postoperative pain during the first active motion at 6 h after surgery assessed using a visual analog scale (VAS).;

Secondary

MeasureTime frame
Resting VAS scores at PACU and 2, 6, 12, 24, 48 and 72 h after surgery.;VAS scores during motion at 12, 24, 48, and 72 h after surgery.;Intraoperative consumption of opioids.;Postoperative consumption of morphin hydrochloride.;Times of sleep interruption due to pain on the night of surgery.;Time until the first walkout of bed after surgery.;Adverse effects associated with analgesias such as postoperative dizziness, nausea, vomiting, wound swelling, wound ooze, drowsiness, urinary retention, and falls after surgery were recorded.;

Countries

China

Contacts

Public ContactYang Jing

West China Hospital, Sichuan University

422963362@qq.com+86 18980602269

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026