osteoarthritis of the hip, osteonecrosis of the femoral head (Ficat IIIB or IV), and developmental dysplasia of the hip.
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1) 18-80 years of age; 2) body mass index (BMI) of 20-35 kg/m2; 3) an American Society of Anesthesiologists (ASA) functional status of II-III; 4) primary unilateral total hip arthroplasty.
Exclusion criteria
Exclusion criteria: 1) hip ankylosis; 2) known allergy to the drugs used in this study; 3) a history of excessive opioid consumption; 4) a history of excessive alcohol consumption; 5) cognitive impairment; 6) psychiatric illness; 7) recognized neuromuscular disorder; 8) previous hip open surgery; 9) other neuropathic diseases of the hip on the target side; 10) inability to communicate verbally.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Postoperative pain during the first active motion at 6 h after surgery assessed using a visual analog scale (VAS).; | — |
Secondary
| Measure | Time frame |
|---|---|
| Resting VAS scores at PACU and 2, 6, 12, 24, 48 and 72 h after surgery.;VAS scores during motion at 12, 24, 48, and 72 h after surgery.;Intraoperative consumption of opioids.;Postoperative consumption of morphin hydrochloride.;Times of sleep interruption due to pain on the night of surgery.;Time until the first walkout of bed after surgery.;Adverse effects associated with analgesias such as postoperative dizziness, nausea, vomiting, wound swelling, wound ooze, drowsiness, urinary retention, and falls after surgery were recorded.; | — |
Countries
China
Contacts
West China Hospital, Sichuan University