osteoporosis/back pain
Conditions
Interventions
Sponsors
Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine
Eligibility
Sex/Gender
Female
Age
45 Years to 75 Years
Inclusion criteria
Inclusion criteria: ? Meet the diagnostic criteria of osteoporosis; ? Meet the diagnostic criteria of liver and kidney insufficiency syndrome; ? Women have been menopausal for more than 1 year and aged from 45 to 75 years; ? Have low back pain more than 3 months and VAS scores>=3?; ? Signing of informed consent.
Exclusion criteria
Exclusion criteria: ? Patients with diseases that can cause secondary osteoporosis such as osteomalacia or multiple myeloma, and other diseases that affect bone metabolism. ? Spinal tuberculosis tumor osteomyelitis and other diseases which are difficult to evaluate the effectiveness of drugs. ? Abnormal serum calcium or parathyroid hormone (serum calcium level is higher than the upper limit of normal, and parathyroid hormone (PTH) is 1.5 times higher than the upper limit of normal). ? Patients with severe primary diseases such as epilepsy, severe cardiovascular and cerebrovascular diseases, abnormal liver and kidney functions, hematopoietic system, or serious diseases (such as tumor, etc.) that affect their survival or patients with psychosis. ? Allergic constitution or allergy to multiple drugs or foods or known allergy to research drugs and their ingredients. ? Patients enrolled in other clinical trials within the last month. ? Patients with contraindications to MRI. ? Patients who the researchers considered inappropriate to participate.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pain VAS;functional magnetic resonance imaging; | — |
Secondary
| Measure | Time frame |
|---|---|
| Bone mineral density;TCM score;SF-12;bone metabolic markers;Hospital Anxiety and Depression Scale;Roland-Morris ???????; | — |
Countries
China
Contacts
Public ContactPang Jian
Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine
Outcome results
None listed