Nasopharyngeal carcinoma
Conditions
Interventions
Treatment Group: thioepipstatin
Sponsors
Zhejiang Province Cancer Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Aged 18 to 70 years, both men and women; 2. Histological or cytologically confirmed locally advanced (stage III~IV) nasopharyngeal carcinoma; 3. The patient intends to receive induction chemotherapy or receive neutropenia or FN during the treatment of the above-mentioned regimen; 4. ECOG PS score = 90 g / L; WBC >= 4.0 x 10^9 / L; ANC >= 2.0 x 10^9 / L; PLT >= 100 x 10^9 / L b) Liver function, biochemical examination: ALT and AST <= 1.5 x ULN; total bilirubin <= 1.5 x ULN; serum creatinine (Cr) <= 1.5 x ULN. 8. Patients with good compliance, volunteered to join the study, signed informed consent; 9. Patients who the investigator believes can benefit;
Exclusion criteria
Exclusion criteria: 1. Pregnant or lactating women; 2. Previously suffered from other malignant tumors (except for stage I non-melanoma skin cancer or cervical carcinoma in situ); 3. Have received radiotherapy or chemotherapy before enrollment; 4. Clinical diagnosis of splenomegaly; 5. According to the investigator's judgment, there are serious concomitant diseases that seriously endanger the patient's safety or affect the patient's completion of the study; 6. Those who are allergic to research drugs, polyethylene glycol recombinant human granulocyte stimulating factor, recombinant human granulocyte stimulating factor, and other preparations for expression of E. coli; 7. Persons with a history of psychotropic substance abuse who are unable to quit or have a mental disorder; 8. The investigator judges other situations that may affect the clinical study and the results of the study, and are not suitable for inclusion in the study; 9. HIV positive patients (except HIV patients with malignant lymphoma); 10. Patients who are considered by the doctor to be unsuitable for the study drug.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| FN Incidence rate; | — |
Countries
China
Contacts
Public ContactChen Xiaozhong
Zhejiang Province Cancer Hospital
Outcome results
None listed