Dry Eye with Meibomian Gland Dysfunction
Conditions
Sponsors
Longhua Hospital Shanghai University of Traditional Chinese Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1. Compliance with MGD diagnostic criteria; 2. Aged 18 to 70years; 3. To be willing and able to cooperate with study requirements; 4. Agreed to use a reliable form of contraception if of childbearing potential.
Exclusion criteria
Exclusion criteria: Had active ocular diseases, excluding glaucoma, or infections other than blepharitis; Had ocular surgery within the past 3 months; Had active ocular allergies; Had autoimmune disease requiring systemic treatment; Was unwilling or unable to discontinue the following medications during the study or during a 30-day washout period before the start of the study: systemic or ocular antibiotics, systemic or ocular steroids, anticholinergics,systemic or ocular antihistamines, ocular nonsteroidal antiinflammatory preparations, ocular vasoconstrictors, and investigational drugs other than the study drug; Pregnant or nursing.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| ocular symptom scores;international ocular surface disease index(OSDI); | — |
Secondary
| Measure | Time frame |
|---|---|
| corneal fluorescein staining(CFS);tear break-up time, BUT;schirmer scores with no anaesthetic (schirmer I test,SIT);the quality of expressed meibum;meibum expressibility; | — |
Countries
China
Contacts
Public ContactXinquan Liu
LongHua Hospital Shanghai University of Traditional Chinese Medicine
Outcome results
None listed