Lymph node metastasis in breast cancer
Conditions
Interventions
1:Vertical method
2:Rotation method
3: Mixed method
A:Short diameter is less than 5mm
B:Short diameter between 5mm to 10mm
C:Short diameter more than 10mm
Sponsors
the Third Affiliated Hospital of Guangzhou Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Patients with a history of breast cancer: including patients who newly diagnosed breast cancer, patients who have undergone breast cancer surgery or chemotherapyneoadjuvant therapy; 2. Patients who agree to participate in this clinical study and sign an informed consent form; 3. Male and female aged 18-75 years old; 4. Patients who have undergone for axillary lymph node dissection, but lymph nodes appear again in the armpit; 5. Patients with abnormal axillary lymph nodes that need to be diagnosed or differentially diagnosed,the ultrasond diagnostic criteria for abnormal lymph nodes are as follows: (1) Lymph node transverse diameter > 10mm (neck lymph node transverse diameter > 7mm) or aspect ratio < 2; (2) The edge of the lymph nodes is irregular; (3) Lymphatic structure disappear; (4) lymph node cortical thickness is greater than 1/2 of the lymph node diameter; (5) The echoes in the lymph nodes are uneven, and there is a focal echo-free zone or a strong echo in the spot; (6) Edematous adjacent soft tissue, lymph nodes merge with each other; (7) Lymph nodes compress peripheral tissues or blood vessels; 6. Agree to surgically remove abnormal lymph nodes.
Exclusion criteria
Exclusion criteria: (1) Those who are allergic to local anesthetics(such as lidocaine ) or who used to have severe drug allergic reactions; (2) Those who cannot tolerate ultrasound interventional surgery; (3) Those who have history of severe cardiovascular disease (such as treatment-requiring arrhythmia or anginacoronary stentingangioplastycoronary artery bypass grafting); cardiac insufficiency (EF<60%); (4) Those who have previous history or complications of arterial thrombosis (such as cerebral thrombosis, transient ischemic attack or myocardial infarction)venous thrombosis (such as deep vein thrombosis, pulmonary embolism); (5) Anticoagulant or antiplatelet drugs are being used 2 weeks before surgery(such as aspirin, warfarin, clopidogrel, heparin, rivaroxaban (Saban), dipyridamole, cilostazoletc.fibrinolytic drugs such as urokinase); (6) Those who have previous history of coagulation abnormalities or abnormal blood coagulation, such as prothrombin time- international normalized ratio (PT-INR), activated partial thromboplastin time (APTT) values outside the normal range of 20%An abnormal increase of D-Dimer (7) Patients who have bleeding disorders (such as immune thrombocytopenia ITPplatelets <50 * 10^9/L); (8) Patients who are not suitable for the trial; (9) Those who have participated in other clinical research within 3 months before the election; (10) Those who are obviously infected with the puncture site; (11) Those who refuse surgery.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Comparison of fine needle puncture and surgical pathology;Positive rate of different lymph node size;Effectiveness of different puncture methods; | — |
Countries
China
Contacts
Public ContactLiang Weixiang
the Third Affiliated Hospital of Guangzhou Medical University
Outcome results
None listed