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Study for the mechanism of improving articular cartilage degeneration by blood flow restriction exercise combined with intra-articular injection of platelet-rich plasma

Study for the mechanism of improving articular cartilage degeneration by blood flow restriction exercise combined with intra-articular injection of platelet-rich plasma

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR1900025420
Enrollment
Unknown
Registered
2019-08-26
Start date
2019-08-22
Completion date
Unknown
Last updated
2019-11-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Articular cartilage degeneration

Interventions

BP:PRP injection and BFR exercise
BN:???????
NC:Routine rehabilitation training

Sponsors

Tianjin Hospital
Lead Sponsor

Eligibility

Sex/Gender
Male
Age
20 Years to 40 Years

Inclusion criteria

Inclusion criteria: 1. Aged 30 + 10 years; 2. Unilateral anterior fork ligament injury and meniscus injury; 3. KOOS-ADL score < 83.2 and pain < 75.8.

Exclusion criteria

Exclusion criteria: 1. The patients had previous osteoarthritis, rheumatoid arthritis and other diseases related to joint damage and related surgery; 2. The patients had tuberculosis, gout, cerebrovascular disease, liver, kidney disease, malignant tumors or other systemic malignant diseases; 3. After injury, the patients received other treatments besides anterior cruciate ligament reconstruction, or injected hormones, sodium hyaluronate and other drugs.

Design outcomes

Primary

MeasureTime frame
KOOS-Pain scale;KOOS-ADL scale;Articular cartilage-T2 mapping;—

Secondary

MeasureTime frame
isokinetic test;SOD in synovial fluid;—

Countries

China

Contacts

Public ContactQi Li

Tianjin Hospital

liqi_82@126.com+86 15022095665

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026