Osteoarthritis of the knee
Conditions
Interventions
D:Adductor canal block +IPACK block
S:Adductor canal block +IPACK block+Dexamethasone is used around the nerve
Sponsors
Department of Anesthesiology, West China Hospital, Sichuan University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: (1) patients requiring unilateral initial TKA surgery ; (2) aged 18 to 80 years; (3) body mass index was 20~35 kg/m2; (4) the American Society of Anesthesiologists (ASA) classification (anesthesia risk assessment) is I ~ III level; (5) the patient signed the informed consent.
Exclusion criteria
Exclusion criteria: (1) there were more than moderate intraoperative knee malformations (pronation and flexion malformations) and joint stiffness; (2) surgical history of knee joint and surgical limb neuropathy; (3) alcohol or drug abuse and and allergic to any drugs in this trial,Contraindicated use of glucocorticoids; (4) long-term opioid users(opioids were used daily or almost daily for more than 3 months); (5) language impairment and inability to perform pain numerical scales (NRS); (6) local skin infection and bleeding at the puncture site of anesthesia; (7) patients considered unfit for inclusion by the surgeon or anesthesiologist.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Time of first postoperative analgesia; | — |
Secondary
| Measure | Time frame |
|---|---|
| Postoperative dosage of remedial morphine hydrochloride;NRS pain score;Range of knee motion;Quadriceps strength;Daily walking distance;Incidence of postoperative complications;QoR -15 scale;Time to gastrointestinal recovery; | — |
Countries
China
Contacts
Public ContactJing Yang
West China Hospital, Sichuan University
Outcome results
None listed