Long non-coding XIST raises methylation of TIMP-3 promoter to regulate collagen degradation in osteoarthritic chondrocytes after tibial plateau fracture

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Observational

Source

ChiCTR

Registry ID

ChiCTR1900025349

Enrollment

Unknown

Registered

2019-08-24

Start date

2016-07-10

Completion date

Unknown

Last updated

2019-08-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

tibial plateau fracture

Interventions

OA:NA

Normal:NA

Eligibility

Sex/Gender

All

Age

36 Years to 52 Years

Inclusion criteria

Inclusion criteria: OA patients who had undergone a surgical procedure for tibial plateau fracture; non-OA patients following an amputation due to trauma

Exclusion criteria

Exclusion criteria: NA

Design outcomes

Primary

Measure	Time frame
mRNA expression;	—

Countries

China

Contacts

Public ContactHongwei Chen

Yiwu Central Hospital, Affiliated Hospital of Wenzhou Medical University

drhongweichen@163.com+86 13506896988

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026