sepsis
Conditions
Interventions
oXiris group:CVVH with oXiris filter
standard group:CVVH with traditional haemofilters
Sponsors
The Sixth Affiliated Hospital of Sun Yat-sen University
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: (1) Diagnosed with cIAI, which may be characterized as manifesting secondary or tertiary peritonitis, single or multiple intra-abdominal abscesses, or an intra-abdominal phlegmon; (2) Diagnosis of septic shock that can be identified with a clinical construct of sepsis with persisting hypotension requiring vasopressors to maintain MAP>=65mmHg and having a serum lactate level>2mmol/L (18mg/dL) despite adequate volume resuscitation; (3) Diagnosis of acute kidney injury (AKI), reaching more than grade 1 according to AKIN, and receiving CVVH.
Exclusion criteria
Exclusion criteria: (1) Patients with irreversible or terminal illness; (2) The willingness to stop or cancel maintaining life (giving up treatment); (3) Pregnant or lactating women; (4) Patients less than 18 years old.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| VDI value; | — |
Countries
China
Contacts
Public ContactQiuye Kou
The Sixth Affiliated Hospital of Sun Yat-sen University
Outcome results
None listed