Impact of preprocedure different concentration simethicone (200mg vs. 1200mg) on bowel preparation and adenoma detection rate: a prospective randomized controlled trial

Status

Recruiting

Phases

Phase 4

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR1900025291

Enrollment

Unknown

Registered

2019-08-21

Start date

2019-09-01

Completion date

Unknown

Last updated

2019-08-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

colonic adenoma

Interventions

low concentration simethicone:simethicone 200mg

high concentration simethicone:simethicone 1200mg

Eligibility

Sex/Gender

All

Age

18 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. Adult patients aged 18 and 80 years; 2. Scheduled for colonoscopy; 3. Written informed consent.

Exclusion criteria

Exclusion criteria: 1. Allergy to simethicone. 2. A history of colon surgery. 3. Familial polyposis. 4. P-J syndrome. 5. Pregnancy. 6. Inflammatory bowel disease. 7. Colon cancer.

Design outcomes

Primary

Measure	Time frame
Boston score;Bubble score;Adenoma detection rate;	—

Secondary

Measure	Time frame
Polyp detection rate;Cecal intubation rate;Withdrawal time;SSP/SSA detection rate;Advent events;	—

Countries

China

Contacts

Public ContactLisheng Wang

The Second Clinical Medicine College (Shenzhen People's Hospital) of Jinan University

wangls168@163.com+86 13714725662

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026