Diabetic Kidney Disease
Conditions
Interventions
losartan potassium:100mg / dose, 1 time / day, orally after meals
Abelmoschus manihot:2.5g / dose, 3 times / day, orally after meals
Sponsors
Shanghai Sixth People's Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Diabetes diagnosis; 2. Diabetic Kidney Disease III periody diagnosis (two positive results out of examinations on three different days); 3. Aged 18-75 years, no gender specified; 4. Blood pressure effectively controlled = 60mL/min; 6. HbA1c <= 9%; 7. Informed consent signed.
Exclusion criteria
Exclusion criteria: 1. Known non-diabetes secondary renal disease; 2. History of Abelmoschus Manihot,ACEI and/or ARB drugs within 1 month prior to enrollment; 3. History of glucocorticoids, immunosuppressive agents or Tripterygium Wilfordii Hook F (TwHF) within 1 month prior to enrollment; 4. Unstable angina pectoris, myocardial infarction and/or coronary stent implantation within 3 months; 5. Liver failure and/or history of hepatic encephalopathy; 6. Malignant tumors or malignant diseases that affect overall prognosis; 7. Triglyceride >= 5.7mmol/L; 8. Pregnancy and lactation; 9. Allergy to losartan potassium or Abelmoschus Manihot; 10. History of unilateral or bilateral renal artery stenosis; 11. Blood pressure < 90/60mmHg; 12. Alcohol or drug use; 13. Participation in other clinical research.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| ACR; | — |
Secondary
| Measure | Time frame |
|---|---|
| eGFR;hs-CRP; | — |
Countries
China
Contacts
Public ContactWeiping Jia
Shanghai Sixth People's Hospital
Outcome results
None listed