asthma,Chronic obstructive pulmonary disease
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Patients with asthma: 1. Meet the diagnostic criteria defined in the GINA2017 guidelines; patients with mild to moderate asthma during the acute attack; currently, asthma is not well controlled (ACT score =30% and predicted 120% of predicted value) and those with obvious dyspnea during activity (Mahler BDI < 8); 3. Volunteer to join the study and sign a written consent form.
Exclusion criteria
Exclusion criteria: Patients with asthma: 1. Patients with poor compliance and speech conversation disorder, patients with a systemic use of glucocorticoids in the past four weeks, patients with structural pulmonary diseases such as chronic obstructive pulmonary disease, bronchiectasis and lung cancer, etc. 2. With severe cardiovascular and cerebrovascular, liver, kidney and hematopoietic system diseases; 3. those with a history of related drug allergy; pregnant women, lactating women or those who cannot exclude pregnancy. Patient with COPD: 1. In addition to COPD, there were other major diseases, such as asthma or bronchitis and other structural lung diseases and lung cancer and other lung substantive diseases; 2. Patients with severe cardiovascular, cerebrovascular, liver, kidney, hematopoietic system diseases; 3. have a history of related drug allergy.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pulmonary function;Clinical symptom score;IgE;Blood routine;CAT score;Chest CT;Blood gas analysis;blood oxygen saturation; | — |
Secondary
| Measure | Time frame |
|---|---|
| Procalcitonin;Inflammatory factor;CRP; | — |
Countries
China
Contacts
the First Affiliated Hospital of Anhui Medical University